Opioid Analgesic REMS: In order that the key benefits of opioid analgesics outweigh the pitfalls of habit, abuse, and misuse, a REMS is required for these products. Below the necessities of the REMS, drug firms with accepted opioid analgesic products must make REMS-compliant education programs available to Health care vendors. https://reidfdavp.blogscribble.com/27958373/promethazine-with-codeine-for-sale-an-overview