The very first asymmetric complete synthesis of conolidine was designed by Micalizio and coworkers in 2011.[2] This synthetic route will allow use of possibly enantiomer (mirror impression) of conolidine via an early enzymatic resolution. Cultures comprised of excitatory neurons, inhibitory neurons and glia self-assemble into spontaneously firing two-dimensional networks https://michaell368rmg6.mycoolwiki.com/user