Arteries are thick-walled vessels meant to deal with significant pressure because they have oxygenated blood clear of the heart. They've 3 layers: Tunica intima: The innermost layer crafted from endothelial cells. Peripheral artery disease: Leg agony or cramps with exercise but strengthen with relaxation; changes in pores and skin shade; https://www.sgvascularctr.com/an-introduction-to-vascular-surgery-in-singapore/